Cancer types | CircRNAs | Roles of circRNAs in m6A | Functions | Mechanisms | Ref. |
---|---|---|---|---|---|
Glioma | circ_0072083 | Promotes ALKBH5 expression via sponging miR-1252-5p | Temozolomide resistance | Maintains glioma stem cells | [198] |
CRC | circPTK2 | Elevates YTHDF1 level by targeting miR-136-5p | 5-FU/oxaliplatin resistance | – | [199] |
HCC | circRHBDD1 | Recruits YTHDF1 | Anti-PD-1 therapy resistance | Elevates glycolysis | [200] |
BC | circ0008399 | Facilitates the formation of MTC through combining with WTAP | Cisplatin resistance | Boosts anti-apoptosis | [201] |
 | circMORC3 | Interacts with VIRMA and elevates global m6A level | Cisplatin resistance | Promotes DNA repair and suppresses DNA damage | [202] |
Prostate cancer | circARHGAP29 | Interacts with IGF2BP2 | Docetaxel resistance | Promotes glycolysis | [156] |