Fig. 1
From: CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma
The expression of CDC6 in different human cancers and its relationship with glioma prognosis. A PCA plot of the data showing no batch effect in the GSE104291 dataset. Red nodes represent the tumor cluster while blue nodes represent the normal cluster. B The volcano plots of DEGs in GSE104291. Red nodes represent upregulated genes, blue nodes represent downregulated genes, and gray indicates genes with no differential expression based on the criteria of p value < 0.05 and |log2 FC| > 1, respectively. C Wilcoxon rank sum test was used to analyze the differential expression of CDC6 in glioma tissues and normal tissues with the data of the GTEx database as controls. D CDC6 expression in TCGA tumors and normal tissues with the data of the GTEx database as controls. E Kaplan–Meier analysis of association between CDC6 expression and glioma prognosis in TCGA. F Kaplan–Meier analysis of association between CDC6 expression and glioma prognosis in CGGA. PCA, principal component analysis; DEGs, differentially expressed genes; log2 FC, log2 foldchange; TCGA, The Cancer Genome Atlas; GTEx, Genotype-Tissue Expression; CGGA, Chinese Glioma Genome Atlas. ns, p ≥ 0.05, *p < 0.05, **p < 0.01, ***p < 0.001