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Fig. 1 | Molecular Cancer

Fig. 1

From: Targeting KRAS mutant cancers: from druggable therapy to drug resistance

Fig. 1

Types and proportion of KRAS mutations in multiple human cancers. a Mutations of KRAS occur in different types of cancers. Data derived from the AACR GENIE 9.0 public database. b Distribution of KRAS alleles in selected tumor types. The top 6 alleles with the highest overall disease rate are listed, while the other mutations were classified in the ‘other’ category. Mutation rates for KRAS were acquired from the Cancer Facts & Figs. 2000 report published by the American Cancer Society and published articles [26]. CRC, colorectal cancer; LUAD, lung adenocarcinoma; PDAC, pancreatic ductal adenocarcinoma; IDC, invasive ductal carcinoma; STAD, stomach adenocarcinoma; UEC, undifferentiated endometrial carcinoma; EAC/GEJC, esophageal adenocarcinoma/gastroesophageal junction cancer

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