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Fig. 2 | Molecular Cancer

Fig. 2

From: A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer

Fig. 2

EGF- and EpEX-treatment associated GSEA and DEGs. A GSEA were performed for Kyse30 and FaDu cells at 6 h and 72 h after the indicated treatment (EGFlow: EGFL, EGFhigh: EGFH, EpEX, EGFhigh with EpEX: EGF_w_EpEX) using MSigDB hallmark gene sets. Significantly activated or suppressed hallmarks are depicted with gene ratios and adjusted p-values. B Venn diagram of DEGs (|log2FC|> 0.5; adjusted p-value ≤ 0.05) at 6 h and 72 h for Kyse30 and FaDu cells under indicated treatments. C Upset plot displays exclusive DEGs in combinations (connected bullet points). Numbers of exclusive DEGs are indicated

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Molecular Cancer

ISSN: 1476-4598