Skip to main content
Fig. 2 | Molecular Cancer

Fig. 2

From: An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer

Fig. 2

Performance evaluation of novel combination panel and risk-stratification model in predicting lymph node metastasis from high-risk T1 CRC patients. A A receiver operating characteristic curve analysis to compare the performance of the combination panel, key pathological features, and risk-stratification model in a validation cohort. B Decision curve plotting net benefit (detection of lymph node metastasis) against threshold probability. C Decision curve plotting net benefit untreated (avoidance of unnecessary operation) against threshold probability. D Comparison of overtreatment frequency between current guidelines and our risk-stratification model. NPV: negative predictive value, PPV: positive predictive value, LNN: lymph node metastasis negative, LNP: lymph node metastasis positive, AUC: area under the curve

Back to article page

Molecular Cancer

ISSN: 1476-4598