Subunit | Biological process | Refs. |
---|---|---|
ACTL6A | Maintenance of hematopoietic stem cells (HSCs) | [54] |
ARID1A | Maintenance of HSCs and differentiation of both myeloid and lymphoid lineages | [55] |
T cell development | [59] | |
ARID1B | Erythropoiesis | [68] |
ARID2 | Maintenance of HSCs and erythropoiesis | [37] |
Regeneration of lymphoid lineage | [35] | |
BCL11A | B-cell and T-cell development | [71] |
Regulation of ɣ-globin gene | ||
Maintenance of HSCs | [76] | |
BCL11B | Thymocyte differentiation | [77] |
BRD9 | Functional modulation of Regulatory T (T-reg) cells | [78] |
PBRM1 | Maintenance of HSCs | [56] |
PHF10 | Maintenance of HSCs and myeloid lineage development | [57] |
SMARCA2 | Regulatory function in HSCs and HPCs (hematopoietic progenitor cells) | [58] |
SMARCA4 | Erythroid development | |
Granulocytic maturation | [63] | |
T-cell differentiation | ||
Development of pro-B cells | [67] | |
Formation and maintenance of HPCs | [79] | |
Myeloid lineage differentiation | [80] | |
SMARCC1 | Development of pro-B cells | [67] |
Thymocyte maturation | [81] | |
SMARCD2 | Granulocytic maturation | |
SMARCE1 | T-cell differentiation | [64] |