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Fig. 3 | Molecular Cancer

Fig. 3

From: Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment

Fig. 3

Crosstalk between CSCs and TME cells. CSCs secrete exosome regulated infltrating immune cells (IICs), MDSC, DC, macrophage and neutrophils to the TME. Cell–cell interactions in TME contribute to the development of cancer. The mechanism of interaction between CSCs and tumor-infiltrating immune cells is not only through immune targets, but can likewise be through exosomes that enable a large exchange

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Molecular Cancer

ISSN: 1476-4598