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Table 2 Types of the post-translational modifications and the modification sites of B7-H3. ( J. Proteome Res. 2009, 8, 2, 651–661; Nat Commun (2021) 12(1):2672)

From: New frontiers in immune checkpoint B7-H3 (CD276) research and drug development

PTMs Residue

PTMS Class

PTM Peptides

N91

N-Glycosylation

ANRTALFPDLLA QGNASL

N104

N-Glycosylation

AQGNASLRL

N189

N-Glycosylation

TGNVTTSQMANEQGLF

N215

N-Glycosylation

RVVLGANGTYSCL

N322

N-Glycosylation

PDLLAQGNASLRLQR

N407

N-Glycosylation

QGVPLTGNVTTSQMA

N433

N-Glycosylation

LRVVLGANGTYSCLV

S513-p

Phosphorylation

QDGEGEGsKtALQPL

T515-p

Phosphorylation

GEGEGsKtALQPLkH

K521-ub

ubiquitination

KtALQPLkHsDskED

K526-ub

ubiquitination

PLkHsDskEDDGQEI