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Fig. 3 | Molecular Cancer

Fig. 3

From: The function and mechanisms of action of circular RNAs in Urologic Cancer

Fig. 3

Biological functions of circRNAs in bladder cancer (BCa)

(A) CircRNAs are involved in the cell proliferation and cycle of BCa. CircSETD3, circ0068307, circ0030586, and circ0041103 affect the cell proliferation of BCa cells by regulating the expression of miRNAs and related proteins. (B) CircRNAs are involved in the metastasis and EMT of BCa. CircTRPS1, circKDM4C, circITCH, and circACVR2A affect the cell metastasis and EMT of BCa cells by regulating the expression of miRNAs and related proteins. (C) CircRNAs are involved in the apoptosis of BCa. CircCEP128, circ001418, circ0058063, and circ0000326 affect the cell apoptosis of BCa cells by regulating the expression of miRNAs and related proteins. (D) CircRNAs are involved in the drug resistance of BCa. Circ102336, circ0008399, and circ0058063 affect the drug resistance of BCa cells by regulating the expression of miRNAs and related proteins

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