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Fig. 4 | Molecular Cancer

Fig. 4

From: The function and mechanisms of action of circular RNAs in Urologic Cancer

Fig. 4

Biological functions of circRNAs in prostate cancer (PCa)

(A) CircRNAs are involved in the cell proliferation and cycle of PCa. CircTRPS1, circPAPPA, circ0076305, and circSLC19A1 affect the cell proliferation of PCa cells by regulating the expression of miRNAs and related proteins. (B) CircRNAs are involved in the metastasis and EMT of PCa. CircPRKCI, circ0062020, circ0004296, and circ0016068 affect the cell metastasis and EMT of PCa cells by regulating the expression of miRNAs and related proteins. (C) CircRNAs are involved in the apoptosis of PCa. Circ0074032, circ0062019, circ0088233, and circ0075542 affect the cell apoptosis of PCa cells by regulating the expression of miRNAs and related proteins. (D) CircRNAs are involved in the drug resistance of PCa. CircRNA17 and circXIA affect the drug resistance of PCa cells by regulating the expression of miRNAs and related proteins

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