Fig. 8
From: Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma
Mouse xenograft models of NK-S1-scramble and NK-S1-TOX2-sh1 cells. A The tumor volume was measured by caliper every 2 -3 days. The tumor growth curves were constructed according to the average tumor volume of each group ± SD (mm3). B Mice were sacrificed, and then the images of xenograft tumors were captured after dissection. Scale bar, 1 cm. C Tumor weights of NK-S1 xenografts in scramble (control) verse TOX2-sh1 group. N = 5. **p < 0.01; ***p < 0.001; ****p < 0.0001. D Schematic representation of molecular mechanism involving in TOX2-SE-driven oncogenesis in NKTL