Fig. 4From: The tumor ecosystem in head and neck squamous cell carcinoma and advances in ecotherapyCrosstalk between tumor cells and T cells. IL-23 and -6 secreted by tumor cells recruit Th17, whereas the ratio of Th17 and Tregs influence HNSCC progression. Abbreviations: IL-6, interleukin-6; FGL1, fibrinogen-like protein 1; LAG-3, lymphocyte activated gene-3; PD-1, programmed cell death protein-1; PD-L1/2, programmed death-ligand 1/2; Th17, T helper 17; TIM-3, T cell immunoglobulin mucin-3Back to article page