Table 2 Changes of major immune cell infiltration compared with normal tissue
From: The tumor ecosystem in head and neck squamous cell carcinoma and advances in ecotherapy
Cell types | HPV-positive | HPV-negative |
|---|---|---|
CD4+ T cells | ↑ | ↓ |
Th1 cells | ↑ | ↑ |
Th2 cells | ↑↑ | ↑↑ |
Tregs | ↑ | - |
CD8+ T cells | ↑↑ | ↑ |
B cells | ↑↑ | - |
DCs | - | - |
NK cells | - | ↓ |
NKT cells | ↑↑ | ↑ |
Neutrophils | - | - |
Monocytes | - | - |
Macrophages | ↑↑ | ↑ |
Plasma cells | ↑↑ | - |