Fig. 2
From: CircZBTB44 promotes renal carcinoma progression by stabilizing HK3 mRNA structure
CircZBTB44 promoted RCC cell malignancyin vitro. (A) The transfection efficiency of si-circZBTB44-1/-2/-3 as well as the effect of si-circZBTB44-1/-2/-3 on ZBTB44 mRNA expression in RCC cells were analyzed by qRT-PCR. (B) CCK-8 and (C) EdU assays were used to detect the impact of circZBTB44 knockdown on RCC cell viability and proliferation. (D) Transwell and (E) wound healing assays were used to detect RCC cell migration after circZBTB44 knockdown. (F) qRT-PCR was used to detect the expression of circZBTB44 in xenografts of indicated groups. (G) Xenografts from different groups. (H) Mouse tumor weight and (I) volume in each group. (J) IHC assays were performed to detect the protein expression of Ki-67 in mouse tumor tissues. *P < 0.05, ***P < 0.001