Skip to main content

Articles

Page 12 of 65

  1. The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna for the development of the Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease9 (CRI...

    Authors: Huimin Zhang, Chunhong Qin, Changming An, Xiwang Zheng, Shuxin Wen, Wenjie Chen, Xianfang Liu, Zhenghua Lv, Pingchang Yang, Wei Xu, Wei Gao and Yongyan Wu
    Citation: Molecular Cancer 2021 20:126
  2. In early-stage mycosis fungoides (MF), the most common primary cutaneous T-cell lymphoma, limited skin involvement with patches and plaques is associated with a favorable prognosis. Nevertheless, approximately...

    Authors: Katharina Rindler, Constanze Jonak, Natalia Alkon, Felix M. Thaler, Harald Kurz, Lisa E. Shaw, Georg Stingl, Wolfgang Weninger, Florian Halbritter, Wolfgang M. Bauer, Matthias Farlik and Patrick M. Brunner
    Citation: Molecular Cancer 2021 20:124
  3. Metabolic reprogramming sustains tumorigenesis and aggressiveness of neuroblastoma (NB), the most common extracranial malignancy in childhood, while underlying mechanisms and therapeutic approaches still remai...

    Authors: Feng Yang, Anpei Hu, Yanhua Guo, Jianqun Wang, Dan Li, Xiaojing Wang, Shikai Jin, Boling Yuan, Shuang Cai, Yi Zhou, Qilan Li, Guo Chen, Haiyang Gao, Liduan Zheng and Qiangsong Tong
    Citation: Molecular Cancer 2021 20:123
  4. N6-methyladenosine (m6A) is a prevalent internal modification in eukaryotic RNAs regulated by the so-called “writers”, “erasers”, and “readers”. m6A has been demonstrated to exert critical molecular functions in ...

    Authors: Xin Wang, Rui Ma, Xilin Zhang, Lian Cui, Yangfeng Ding, Weimin Shi, Chunyuan Guo and Yuling Shi
    Citation: Molecular Cancer 2021 20:121
  5. Cancer cells develop resistance to chemotherapeutic intervention by excessive formation of stress granules (SGs), which are modulated by an oncogenic protein G3BP2. Selective control of G3BP2/SG signaling is a...

    Authors: Haichang Li, Pei-Hui Lin, Pranav Gupta, Xiangguang Li, Serena Li Zhao, Xinyu Zhou, Zhongguang Li, Shengcai Wei, Li Xu, Renzhi Han, Jing Lu, Tao Tan, Dong-Hua Yang, Zhe-Sheng Chen, Timothy M. Pawlik, Robert E. Merritt…
    Citation: Molecular Cancer 2021 20:118
  6. Adenosine deaminases acting on RNA (ADARs) modify many cellular RNAs by catalyzing the conversion of adenosine to inosine (A-to-I), and their deregulation is associated with several cancers. We recently showed...

    Authors: Julia Ramírez-Moya, Christos Miliotis, Allison R. Baker, Richard I. Gregory, Frank J. Slack and Pilar Santisteban
    Citation: Molecular Cancer 2021 20:115
  7. Circular RNAs (circRNAs) play important roles in cancer progression and metabolism regulation. Serine/glycine metabolism supports the growth of cancer cells by contributing to their anabolic demands and epigen...

    Authors: Xin Liu, Yunze Liu, Zhao Liu, Changwei Lin, Fanchao Meng, Lei Xu, Xiuzhong Zhang, Chong Zhang, Penbo Zhang, Shuai Gong, Nai Wu, Zeqiang Ren, Jun Song and Yi Zhang
    Citation: Molecular Cancer 2021 20:114
  8. Extrachromosomal circular DNA (eccDNA) refers to a type of circular DNA that originate from but are likely independent of chromosomes. Due to technological advancements, eccDNAs have recently emerged as multif...

    Authors: Xiaoxuan Ling, Yali Han, Jinxue Meng, Bohuan Zhong, Jialong Chen, He Zhang, Jiheng Qin, Jing Pang and Linhua Liu
    Citation: Molecular Cancer 2021 20:113
  9. Circular RNAs (circRNAs) are widely expressed in human cells and are closely associated with cancer development. However, they have rarely been investigated in the context of nasopharyngeal carcinoma (NPC).

    Authors: Yongzhen Mo, Yumin Wang, Shuai Zhang, Fang Xiong, Qijia Yan, Xianjie Jiang, Xiangying Deng, Yian Wang, Chunmei Fan, Le Tang, Shanshan Zhang, Zhaojian Gong, Fuyan Wang, Qianjin Liao, Can Guo, Yong Li…
    Citation: Molecular Cancer 2021 20:112
  10. Synthetic lethality describes a genetic interaction between two perturbations, leading to cell death, whereas neither event alone has a significant effect on cell viability. This concept can be exploited to sp...

    Authors: Salvatore Benfatto, Özdemirhan Serçin, Francesca R. Dejure, Amir Abdollahi, Frank T. Zenke and Balca R. Mardin
    Citation: Molecular Cancer 2021 20:111
  11. Authors: Yun-ping Hu, Yun-peng Jin, Xiang-song Wu, Yang Yang, Yong-sheng Li, Huai-feng Li, Shan-shan Xiang, Xiao-ling Song, Lin Jiang, Yi-jian Zhang, Wen Huang, Shi-li Chen, Fa-tao Liu, Chen Chen, Qin Zhu, Hong-zhuan Chen…
    Citation: Molecular Cancer 2021 20:110

    The original article was published in Molecular Cancer 2019 18:167

  12. Early recurrence is a major obstacle to prolonged postoperative survival in squamous cell lung carcinoma (SqCLC). The molecular mechanisms underlying early SqCLC recurrence remain unclear, and effective progno...

    Authors: Qingqing Wu, Xiaoyang Luo, Mikkel G. Terp, Qingrun Li, Yuan Li, Lei Shen, Ying Chen, Kirstine Jacobsen, Trever G. Bivona, Haiquan Chen, Rong Zeng and Henrik J. Ditzel
    Citation: Molecular Cancer 2021 20:108
  13. Necroptosis is emerging as a new target for cancer immunotherapy as it is now recognized as a form of cell death that increases tumor immunogenicity, which would be especially helpful in treating immune-desert...

    Authors: Han-Hee Park, Hwa-Ryeon Kim, Sang-Yeong Park, Sung-Min Hwang, Sun Mi Hong, Sangwook Park, Ho Chul Kang, Michael J. Morgan, Jong-Ho Cha, Dakeun Lee, Jae-Seok Roe and You-Sun Kim
    Citation: Molecular Cancer 2021 20:107
  14. Extensive studies have demonstrated the pivotal roles of circular RNAs (circRNAs) in the occurrence and development of different human cancers. However, the expression and regulatory roles of circRNAs in pancr...

    Authors: Zeyin Rong, Si Shi, Zhen Tan, Jin Xu, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu and Chen Liang
    Citation: Molecular Cancer 2021 20:106
  15. An in-depth understanding of immune evasion mechanisms in tumors is crucial to overcome resistance and enable innovative advances in immunotherapy. Circular RNAs (circRNAs) have been implicated in cancer progr...

    Authors: Zhenchuan Liu, Tingting Wang, Yunlang She, Kaiqing Wu, Shaorui Gu, Lei Li, Chenglai Dong, Chang Chen and Yongxin Zhou
    Citation: Molecular Cancer 2021 20:105
  16. Circulating tumor cells are tumor cells with high vitality and high metastatic potential that invade and shed into the peripheral blood from primary solid tumors or metastatic foci. Due to the heterogeneity of...

    Authors: Jiasheng Xu, Kaili Liao, Xi Yang, Chengfeng Wu and Wei Wu
    Citation: Molecular Cancer 2021 20:104

    The Correction to this article has been published in Molecular Cancer 2022 21:100

  17. Constitutive activation of nuclear factor-κB (NF-κB) signaling plays a key role in the development and progression of colorectal carcinoma (CRC). However, the underlying mechanisms of excessive activation of N...

    Authors: Zhen-xing Liang, Hua-shan Liu, Li Xiong, Xin Yang, Feng-wei Wang, Zi-wei Zeng, Xiao-wen He, Xian-rui Wu and Ping Lan
    Citation: Molecular Cancer 2021 20:103
  18. Authors: Tao Zhang, Rong Qu, Shingpan Chan, Mengzhen Lai, Linjiang Tong, Fang Feng, Hongyu Chen, Tingting Song, Peiran Song, Gang Bai, Yingqiang Liu, Yanan Wang, Yan Li, Yi Su, Yanyan Shen, Yiming Sun…
    Citation: Molecular Cancer 2021 20:102

    The original article was published in Molecular Cancer 2020 19:90

  19. Circular RNAs (circRNAs) play important roles in cancer development and progression. The purpose of this study is to identify aberrantly expressed circRNAs in gastric cancer (GC), unravel their roles in GC pro...

    Authors: Yu Zhang, Jiajia Jiang, Jiayin Zhang, Han Shen, Maoye Wang, Zhen Guo, Xueyan Zang, Hui Shi, Jiayan Gao, Hui Cai, Xinjian Fang, Hui Qian, Wenrong Xu and Xu Zhang
    Citation: Molecular Cancer 2021 20:101
  20. 3-phosphoinositide-dependent protein kinase-1 (PDK1) acts as a master kinase of protein kinase A, G, and C family (AGC) kinase to predominantly govern cell survival, proliferation, and metabolic homeostasis. A...

    Authors: Qiwei Jiang, Nana Zheng, Lang Bu, Xiaomei Zhang, Xiaoling Zhang, Yuanzhong Wu, Yaqing Su, Lei Wang, Xiaomin Zhang, Shancheng Ren, Xiangpeng Dai, Depei Wu, Wei Xie, Wenyi Wei, Yasheng Zhu and Jianping Guo
    Citation: Molecular Cancer 2021 20:100
  21. Exosomes are a subpopulation of the tumour microenvironment (TME) that transmit various biological molecules to promote intercellular communication. Exosomes are derived from nearly all types of cells and exis...

    Authors: Xiao-Huan Tang, Ting Guo, Xiang-Yu Gao, Xiao-Long Wu, Xiao-Fang Xing, Jia-Fu Ji and Zi-Yu Li
    Citation: Molecular Cancer 2021 20:99
  22. Breast cancer (BC) has a marked tendency to spread to the bone, resulting in significant skeletal complications and mortality. Recently, circular RNAs (circRNAs) have been reported to contribute to cancer init...

    Authors: Yingru Xu, Shuxia Zhang, Xinyi Liao, Man Li, Suwen Chen, Xincheng Li, Xingui Wu, Meisongzhu Yang, Miaoling Tang, Yameng Hu, Ziwen Li, Ruyuan Yu, Mudan Huang, Libing Song and Jun Li
    Citation: Molecular Cancer 2021 20:98
  23. Authors: Shunya Ohmura, Aruna Marchetto, Martin F. Orth, Jing Li, Susanne Jabar, Andreas Ranft, Endrit Vinca, Katharina Ceranski, Martha J. Carreño-Gonzalez, Laura Romero-Pérez, Fabienne S. Wehweck, Julian Musa, Felix Bestvater, Maximilian M. L. Knott, Tilman L. B. Hölting, Wolfgang Hartmann…
    Citation: Molecular Cancer 2021 20:97
  24. The aim of this study was to identify a urine extracellular vesicle circular RNA (circRNA) classifier that could detect high-grade prostate cancer (PCa) of Grade Group (GG) 2 or greater. For this purpose, we u...

    Authors: Ya-Di He, Wen Tao, Tao He, Bang-Yu Wang, Xiu-Mei Tang, Liang-Ming Zhang, Zhen-Quan Wu, Wei-Ming Deng, Ling-Xiao Zhang, Chun-Kui Shao, Jing Zhou, Li-Min Rong, Xin Gao and Liao-Yuan Li
    Citation: Molecular Cancer 2021 20:96
  25. Colorectal cancer (CRC) is one of the most common malignant tumours. The recurrence and metastasis of CRC seriously affect the survival rate of patients. Angiogenesis is an extremely important cause of tumour ...

    Authors: Yaxin Guo, Yuying Guo, Chen Chen, Dandan Fan, Xiaoke Wu, Luyang Zhao, Bo Shao, Zhenqiang Sun and Zhenyu Ji
    Citation: Molecular Cancer 2021 20:93
  26. Recent studies have revealed that circular RNAs (circRNAs) play significant roles in the occurrence and development of many kinds of cancers including breast cancer (BC). However, the potential functions of mo...

    Authors: Xiaosong Wang, Lei Xing, Rui Yang, Hang Chen, Min Wang, Rong Jiang, Luyu Zhang and Junxia Chen
    Citation: Molecular Cancer 2021 20:91
  27. As the main protein components of chromatin, histones play central roles in gene regulation as spools of winding DNA. Histones are subject to various modifications, including phosphorylation, acetylation, glyc...

    Authors: Dongwei Zhu, Yue Zhang and Shengjun Wang
    Citation: Molecular Cancer 2021 20:90
  28. Cancer metastases are the main cause of lethality. The five-year survival rate for patients diagnosed with advanced stage oral cancer is 30%. Hence, the identification of novel therapeutic targets is an urgent...

    Authors: Jonas Weiße, Julia Rosemann, Lisa Müller, Matthias Kappler, Alexander W. Eckert, Markus Glaß, Danny Misiak, Stefan Hüttelmaier, Wolfgang G. Ballhausen, Mechthild Hatzfeld, Monika Haemmerle and Tony Gutschner
    Citation: Molecular Cancer 2021 20:88

    The Correction to this article has been published in Molecular Cancer 2023 22:50

  29. Human T cell Leukemia virus type 1 (HTLV-I) is etiologically linked to adult T cell leukemia/lymphoma (ATL) and an inflammatory neurodegenerative disease called HTLV-I-associated myelopathy or tropical spastic...

    Authors: Marcia Bellon, Izabela Bialuk, Veronica Galli, Xue-Tao Bai, Lourdes Farre, Achilea Bittencourt, Ambroise Marçais, Michael N. Petrus, Lee Ratner, Thomas A. Waldmann, Vahid Asnafi, Antoine Gessain, Masao Matsuoka, Genoveffa Franchini, Olivier Hermine, Toshiki Watanabe…
    Citation: Molecular Cancer 2021 20:86
  30. While immune checkpoint blockade (ICB) is the current first-line treatment for metastatic melanoma, it is effective for ~ 52% of patients and has dangerous side effects. The objective here was to identify the ...

    Authors: Chi Yan, Nabil Saleh, Jinming Yang, Caroline A. Nebhan, Anna E. Vilgelm, E. Premkumar Reddy, Joseph T. Roland, Douglas B. Johnson, Sheau-Chiann Chen, Rebecca L. Shattuck-Brandt, Gregory D. Ayers and Ann Richmond
    Citation: Molecular Cancer 2021 20:85
  31. Multiple myeloma (MM) is still incurable and characterized by clonal expansion of plasma cells in the bone marrow (BM). Therefore, effective therapeutic interventions must target both myeloma cells and the BM ...

    Authors: Chunyan Gu, Wang Wang, Xiaozhu Tang, Tingting Xu, Yanxin Zhang, Mengjie Guo, Rongfang Wei, Yajun Wang, Artur Jurczyszyn, Siegfried Janz, Meral Beksac, Fenghuang Zhan, Anja Seckinger, Dirk Hose, Jingxuan Pan and Ye Yang
    Citation: Molecular Cancer 2021 20:84
  32. Tumor-derived exosomes (TDEs) have been shown to impede anti-tumor immune responses via their immunosuppressive cargo. Since dendritic cells (DCs) are the key mediators of priming and maintenance of T cell-med...

    Authors: Reza Hosseini, Leila Asef-Kabiri, Hassan Yousefi, Hamzeh Sarvnaz, Majid Salehi, Mohammad Esmaeil Akbari and Nahid Eskandari
    Citation: Molecular Cancer 2021 20:83
  33. Liquid biopsy is now considered a valuable diagnostic tool for advanced metastatic non-small cell lung cancer (NSCLC). In NSCLC, circulating tumor DNA (ctDNA) analysis has been shown to increase the chances of...

    Authors: Misako Nagasaka, Mohammed Hafiz Uddin, Mohammed Najeeb Al-Hallak, Sarah Rahman, Suresh Balasubramanian, Ammar Sukari and Asfar S. Azmi
    Citation: Molecular Cancer 2021 20:82
  34. Noncoding RNAs such as circular RNAs (circRNAs) are abundant in the human body and influence the occurrence and development of various diseases. However, the biological functions of circRNAs in colorectal canc...

    Authors: Jiaqi Wang, Yi Zhang, Hu Song, Hang Yin, Tao Jiang, Yixin Xu, Lianyu Liu, Hongyu Wang, Hong Gao, Renhao Wang and Jun Song
    Citation: Molecular Cancer 2021 20:81
  35. Granulocyte-macrophage colony stimulating factor (GM-CSF) is a cytokine that is used as an immunopotentiator for anti-tumor therapies in recent years. We found that some of the extranodal natural killer/T cell...

    Authors: Qi-xiang Rong, Fang Wang, Zhi-xing Guo, Yi Hu, Sai-nan An, Min Luo, Hong Zhang, Shao-cong Wu, Hui-qiang Huang and Li-wu Fu
    Citation: Molecular Cancer 2021 20:80
  36. Somatic mutations are involved in hepatocellular carcinoma (HCC) progression, but the genetic mechanism associated to hepatocarcinogenesis remains poorly understood. We report that Eyes absent homolog 2 (EYA2)...

    Authors: Ze-Kun Liu, Can Li, Ren-Yu Zhang, Ding Wei, Yu-Kui Shang, Yu-Le Yong, Ling-Min Kong, Nai-Shan Zheng, Ke Liu, Meng Lu, Man Liu, Cai-Xia Hu, Xiao-Zhen Yang, Zhi-Nan Chen and Huijie Bian
    Citation: Molecular Cancer 2021 20:79
  37. Distant metastasis is the major cause of death in patients with colorectal cancer (CRC). Previously, we identified KITENIN as a metastasis-enhancing gene and suggested that the oncogenic KITENIN complex is inv...

    Authors: Jeong A Bae, Woo Kyun Bae, Sung Jin Kim, Yoo-Seung Ko, Keon Young Kim, So-Yeon Park, Young Hyun Yu, Eun Ae Kim, Ik Joo Chung, Hangun Kim, Hyung-Ho Ha and Kyung Keun Kim
    Citation: Molecular Cancer 2021 20:78
  38. KDM6A, a histone demethylase, is frequently mutated in bladder cancer (BCa). However, the role and detailed molecular mechanism of KDM6A involved in bladder cancer progression remains unknown.

    Authors: Lei Liu, Jianfeng Cui, Yajing Zhao, Xiaochen Liu, Lipeng Chen, Yangyang Xia, Yong Wang, Shouzhen Chen, Shuna Sun, Benkang Shi and Yongxin Zou
    Citation: Molecular Cancer 2021 20:77

Annual Journal Metrics

  • 2022 Citation Impact
    37.3 - 2-year Impact Factor
    33.1 - 5-year Impact Factor
    5.740 - SNIP (Source Normalized Impact per Paper)
    8.703 - SJR (SCImago Journal Rank)

    2023 Speed
    5 days submission to first editorial decision for all manuscripts (Median)
    91 days submission to accept (Median)

    2023 Usage 
    3,569,666 downloads
    2,070 Altmetric mentions