Figure 4From: Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting systemIn vitro effect of adenoviral vectors carrying the E1A gene. (a) Cell viability was determined by an MTT assay at 72 h after infection with recombinant adenoviral vectors (10 PFU/cell). Graphs are representative of three separate experiments. (b) Apoptosis was investigated using flow cytometric analysis at 72 h after infection with Ad315-E1A, Ad315-EGFP or H101 (10 PFU/cell). The bottom right quadrants in dot plots show the apoptosis of various cell lines infected with Ad315-E1A. Data are representative of three separate experiments.Back to article page