Figure 4
From: Role of SIRT3 in the regulation of redox balance during oral carcinogenesis
ROS levels and cell proliferation are regulated by SIRT3 in OSCCs. (A) Western blotting of whole cell lysates isolated from cells overexpressing flag-tagged SIRT3 and their relative fluorescence after incubation with DHE. C: control; T: transfected cells. (B) Relative activity of SIRT3 in OSCCs. OECM-1 and HSC-3 cell lines were transiently transfected with or without flag-tagged SIRT3. (C) Cell proliferation of SIRT3-overexpressing OSCC cell lines. Each data point represents the mean ± SD from at least 3 independent experiments (mean ± SD). The asterisk indicates a significant difference (*, p < 0.05) compared to control.