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Figure 2 | Molecular Cancer

Figure 2

From: Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancer

Figure 2

In vitro cytotoxity of (Rap) 2 -E1-(Rap) 2 in selected breast cancer cell lines. Cells were cultured for 4Ā days in the presence of (Rap)2-E1-(Rap)2, CH3-AD2-IgG-hRS7, Rap-DDD2, or a combination of hRS7 IgG and Rap-DDD2 at indicated concentrations. Viable cells were determined with the MTS assay, and the results relative to untreated cells were plotted against log of concentrations. Half maximal effective concentration (EC50) values were determined using non-linear regression sigmoidal doseā€“response curve of Prism software.

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Molecular Cancer

ISSN: 1476-4598