Tag SNPs in complement receptor-1 contribute to the susceptibility to non-small cell lung cancer

Table 2 Genotype frequencies of CRI among cases and controls and their association with non-small cell lung cancers

CRI Genotypes	Controls (n = 470)		Cases (n = 470)		OR(95% CI)^*	P
CRI Genotypes	No	(%)	No	(%)	OR(95% CI)^*	P
rs7525160
GG	176	37.5	139	29.6	1.00 (ref.)
CG	228	48.5	256	54.5	1.38 (1.04-1.85)	0.041
CC	66	14.0	75	15.9	1.52 (1.02-2.28)	0.028
rs3886100
GG	117	24.9	105	22.4	1.00 (ref.)
AG	223	47.4	253	53.8	1.33 (0.97-1.81)	0.078
AA	130	27.7	112	23.8	1.06 (0.73-1.54)	0.755
rs11118167
TT	348	74.1	353	75.1	1.00 (ref.)
CT	111	23.6	102	21.7	0.89 (0.65-1.21)	0.457
CC	11	2.3	15	3.2	1.35 (0.61-3.01)	0.461
rs9429782
GG	250	53.2	261	55.5	1.00 (ref.)
GT	220	46.8	209	44.5	0.89 (0.69-1.16)	0.388
rs10494885
CC	178	37.9	164	34.9	1.00 (ref.)
CT	224	47.6	232	49.4	1.11 (0.83-1.47)	0.490
TT	68	14.5	74	15.7	1.20 (0.81-1.78)	0.365
rs7542544
CC	128	27.2	108	23.0	1.00 (ref.)
AC	223	47.5	252	53.6	1.21 (0.88-1.67)	0.239
AA	119	25.3	110	23.4	0.90 (0.62-1.30)	0.897
rs6691117
AA	324	68.9	327	69.6	1.00 (ref.)
AG	131	27.9	128	27.2	0.98 (0.73-1.31)	0.888
GG	15	3.2	15	3.2	0.96 (0.46-2.02)	0.923
rs6656401
GG	436	92.8	447	95.1	1.00 (ref.)
AG	34	7.2	23	4.9	0.68 (0.39-1.18)	0.174
AA	0	0.0	0	0.0	NC^§
rs2296160
CC	185	39.4	194	41.3	1.00 (ref.)
CT	226	48.1	220	46.8	0.91 (0.69-1.21)	0.521
TT	59	12.5	56	11.9	0.90 (0.59-1.37)	0.606
rs9429942
TT	452	96.2	457	97.2	1.00 (ref.)
CT	18	3.8	13	2.8	0.77 (0.37-1.61)	0.482
CC	0	0.0	0	0.0	NC^§
rs4844600
GG	171	36.4	179	38.1	1.00 (ref.)
AG	230	48.9	228	48.5	0.92 (0.70-1.22)	0.571
AA	69	14.7	63	13.4	0.87 (0.58-1.31)	0.513
rs3818361
CC	187	39.8	188	40.0	1.00 (ref.)
CT	224	47.7	224	47.7	0.98 (0.74-1.29)	0.868
TT	59	12.5	58	12.3	0.96 (0.63-1.46)	0.848
rs17048010
TT	301	64.0	286	60.8	1.00 (ref.)
CT	154	32.8	164	34.9	1.09 (0.82-1.43)	0.556
CC	15	3.2	20	4.3	1.40 (0.70-2.79)	0.343

ISSN: 1476-4598