Figure 1
From: SLC/CCL21-mediated anti-tumor responses require IFNγ, MIG/CXCL9 and IP-10/CXCL10
10 5 3 LL tumors were implanted in C57Bl/6 mice. 5 days following tumor implantation, mice were treated intratumorally with recombinant murine SLC/CCL21 (0.5 μg) 3X/week. One day before SLC/CCL21 administration, mice were given the respective cytokine antibody by i.p. injection. The antibodies were administered three times per week. Antibodies to: IP-10/CXCL10, MIG/CXCL9 and IFNγ significantly inhibited the antitumor efficacy of SLC/CCL21 (*p < 0.01 compared to the control antibody treated group). n = 8 mice group