Figure 10From: TGFβ1 signaling via αVβ6 integrinHypothesis about an alternate TGFβ 1 signaling pathway via α V β 6 integrin, independent of RGD. This pathway may be required for full TGFβ1 induced transcriptional activation, which explains the TGFβ1 sensitivity of those cells lacking DPC4/SMAD4 function that still react with growth inhibition.Back to article page