Figure 3

Altered expression of TF antigen in carcinoma cells. A Normal esophagus: Electron micrograph showing lesser expression of TF antigen along the cell membrane (Uranyl acetate and lead citrate staining. Bar scale = 250 nm). B. WD: Electron micrograph showing increased TF antigen expression embedded in the mucinous secretion (Uranyl acetate and lead citrate staining 200 nm). C. WD: Electron micrograph showing cytosol of neoplastic cells with scattered TF antigen expression (Uranyl acetate and lead citrate staining. Bar scale = 250 nm). D. WD:Electron micrograph showing TF antigen positive granules in the near vicinity of mucin in the cytosol (Uranyl acetate and lead citrate staining. Bar scale = 500 nm). E. WD: Electron micrograph showing TF antigen positive granules embedded in the mucin (Uranyl acetate and lead citrate staining. Bar scale = 200 nm). F. WD: Electron micrograph showing TF antigen positive granules abundantly embedded in the mucin (Uranyl acetate and lead citrate staining. Bar scale = 250 nm).