Expression of the Tpl2/Cot oncogene in human T-cell neoplasias

Table 1 Patient characteristics

Patient no.	Disease	Sex	Age	%T+NKcells/PBMC	Disease state	Co-existent conditions
1	SS	F	88	87	PP
2	CTCL with monoclonal T- LGL lymphocytosis	M	63	86	RD
3	T-LGL leykemia	F	75	93	RD	Neutropenia
4	MF	M	91	71	RD
5	MF	M	85	71	RD
6	TLL	F	35	77	RD
7	T-PLL	M	85	67	RD	Myositis
8	Chronic NK -lymphocytosis	F	67	64	Stable for two years	Neutropenia
9	T-ALL	M	16	95 LB	RD
10	T-LGL leukaemia with reactive NK lymphocytosis	F	60	71	Stable for 10 years	Sarcoidosis (past), neutropenia
11	PTCL secondary to MF	M	52	85	PR
12	Pre-T-ALL	M	37	95 LB	RD

Abbreviations: SS, Sezary syndrome; CTCL, Cutaneous T cell Lymphoma; T-LGL, T-large granular lymphocyte; MF, Mucosis Fungoides; NK, natural killer cell; TLL, T-lymphoblastic lymphoma; T-PLL, T-Prolymphocytic leukemia; T-ALL, T-acute lymphoblastic leukemia; LB, Lymphoblast ;PP, primary progressive; RD, recently diagnosed; PR, partial response.

ISSN: 1476-4598