Table 8 Genes significantly decreased in tumors (continued).
From: Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome
GeneBank Accession | Gene Description | Symbol | Normal Mean | Tumor Mean | Fold Change | P value |
|---|---|---|---|---|---|---|
| Â | Other/Undefined | Â | Â | Â | Â | Â |
X72475 | immunoglobulin kappa constant | IGKC | 1409 | 276 | -5.11 | 0.000111 |
D17570 | zona pellucida binding protein | ZPBP | 355 | 71 | -5.02 | 0.001107 |
M90657 | transmembrane 4 superfamily member 1 | TM4SF1 | 592 | 141 | -4.20 | 0.004537 |
AF063308 | mitotic spindle coiled-coil related protein | SPAG5 | 2015 | 502 | -4.01 | 0.000588 |
U66059 | T cell receptor beta locus | TRB@ | 3022 | 779 | -3.88 | 0.000266 |
AL022165 | carbohydrate sulfotransferase 7 | CHST7 | 359 | 94 | -3.82 | 0.001738 |
U10694 | melanoma antigen, family A, 9 | MAGEA9 | 1039 | 272 | -3.82 | 0.000067 |
M73255 | vascular cell adhesion molecule 1 | VCAM1 | 80 | 22 | -3.66 | 0.004179 |
U47926 | leprecan-like 2 protein | LEPREL2 | 1003 | 319 | -3.15 | 0.00013 |
L05424 | CD44 antigen | CD44 | 1439 | 471 | -3.05 | 0.001361 |
AI445461 | transmembrane 4 superfamily member 1 | TM4SF1 | 463 | 161 | -2.88 | 0.002911 |
AF010310 | proline oxidase homolog | PRODH | 1194 | 421 | -2.84 | 0.000005 |
AF000991 | testis-specific transcript, Y-linked 2 | TTTY2 | 700 | 254 | -2.76 | 0.000542 |
X57522 | transporter 1, ATP-binding cassette, sub-family B | TAP1 | 781 | 287 | -2.72 | 0.000971 |
AA314825 | trefoil factor 1 | TFF1 | 1657 | 616 | -2.69 | 0.000011 |
AB020880 | squamous cell carcinoma antigen | SART3 | 3228 | 1224 | -2.64 | 0.000135 |
AF040707 | homologous to yeast nitrogen permease | NPR2L | 1131 | 437 | -2.59 | 0.001537 |
U47292 | trefoil factor 2 | TFF2 | 359 | 141 | -2.54 | 0.000684 |
X69398 | CD47 antigen | CD47 | 350 | 144 | -2.42 | 0.000853 |
U27331 | fucosyltransferase 6 | FUT6 | 1105 | 473 | -2.34 | 0.000872 |
AI827730 | cyclin M2 | CNNM2 | 5863 | 2535 | -2.31 | 0.000484 |
U05255 | glycophorin B | GYPB | 1606 | 717 | -2.24 | 0.00013 |
M34428 | pvt-1 oncogene homolog, MYC activator | PVT1 | 1231 | 550 | -2.24 | 0.004423 |
U86759 | netrin 2-like | NTN2L | 2039 | 937 | -2.18 | 0.000204 |
D90278 | CEA-related cell adhesion molecule 3 | CEACAM3 | 4388 | 2024 | -2.17 | 0.000902 |
L40400 | ZAP3 protein | ZAP3 | 1549 | 719 | -2.15 | 0.000776 |
U48224 | beaded filament structural protein 2, phakinin | BFSP2 | 568 | 271 | -2.10 | 0.000166 |
AI138834 | deltex homolog 2 | DTX2 | 311 | 148 | -2.10 | 0.000687 |
M13755 | interferon-stimulated protein, 15 kDa | G1P2 | 1507 | 741 | -2.03 | 0.001157 |
X52228 | mucin 1, transmembrane | MUC1 | 1523 | 756 | -2.02 | 0.001707 |