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Figure 7 | Molecular Cancer

Figure 7

From: Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells

Figure 7

BCL11A-S is relocalized from the cytoplasm to the nucleus by interaction with BCL11A-XL or BCL11A-L. COS7 cells were transiently co-transfected with GFP-BCL11A-S and either the Gal4DBD as a negative interaction control (A), or with Gal4DBD-BCL11A-XL (B and D) or Gal4DBD-BCL11A-L (C and E). Cells were observed 24 hr after transfection via fluorescence microscopy. Hoescht 33342 staining of corresponding nuclei is shown to the right of each green fluorescence panel.

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