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Figure 4 | Molecular Cancer

Figure 4

From: Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors

Figure 4

Effects of MadMyc chimera expression on CDK, cyclin and CKI proteins. Polyclonal populations of RD cells stably transfected with MadMyc chimera and CMV were plated and harvested after 4 days. Cell lysates were analysed by immunoblotting with specific antibodies for indicated proteins. α-tubulin expression shows equal loading. The histograms (lower panel) show the values of fold increase over the control, arbitrarly set at 1, obtained by densitometric analysis of the immunoblottings. Similar results were obtained in two experiments.

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Molecular Cancer

ISSN: 1476-4598