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Figure 5 | Molecular Cancer

Figure 5

From: Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors

Figure 5

Effects of U0126 and TPA on anchorage independent growth of RD cells. A. RD cells left untreated (C) or treated with U0126 or 10-7 M TPA were tested for growth in soft agar. Colonies were photographed after 14 days. B. Growth curves of adherent and non adherent RD cells left untreated () or treated with U0126 () or TPA (). RD cells were counted at indicated times. The data shown are the mean ± s.e.m. of triplicates of a representative experiment. Similar results were obtained in three experiments for A and two for B.

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