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Figure 1 | Molecular Cancer

Figure 1

From: PTTG expression in different experimental and human prolactinomas in relation to dopaminergic control of lactotropes

Figure 1

Comparative PTTG and pttg mRNA content in pituitaries from wildtype and D2R knockout female mice. A) Comparative pituitary PTTG content (evaluated by Western blot) in wildtype (+/+, filled bars) and D2R knockout (-/-, empty bars) female mice. For each sample, arbitrary units of band intensities for PTTG were divided by band intensities for the respective actin, and compared to those of wildtype females (considered 100%) in each series of experiments. * P < 0.05 vs. +/+; N = 12 and 15, respectively. For this and following figures, results shown are means ± SE. Below, representative western blots. B) Densitometric analysis of pituitary pttg RT-PCR products, in wildtype (filled bars) and D2R knockout (empty bars) female mice. For each sample, intensity units of the pttg band were normalized to those of the respective GAPDH band. * P < 0.05 vs. +/+; N = 5 and 5. Below representative bands are depicted.

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Molecular Cancer

ISSN: 1476-4598