Skip to main content
Figure 8 | Molecular Cancer

Figure 8

From: Differential expression and role of p21cip/waf1 and p27kip1 in TNF-α-induced inhibition of proliferation in human glioma cells

Figure 8

A-B. Induction of p21 and p27 expression by TNF-α does not involve PI3K/Akt pathway. (A) LN-18 cells grown on coverslips, were sensitized with LY294002 (50 μM) for 2 hr and treated with TNF-α (10 ng/ml) for 3 hr and the expression of p21 or (B) p27 was studied by confocal laser scanning microscopy. Cells were stained with p21/p27 antibodies followed by secondary antibody labeled with Cy3. DAPI was used for nuclear staining (blue). Merged images depict nuclear localization for p21 and predominant cytoplasmic localization of p27. (Magnification 63×).

Back to article page

Molecular Cancer

ISSN: 1476-4598