Figure 6

RNA expression in leukemic blasts from AML patients with or without MOZ-TIF2 fusion. RNA was isolated from the leukemic blasts of 5 different patients. RNA was also isolated on three separate occasions from the leukemic blasts of the patient exhibiting the MOZ-TIF2 fusion. RT-PCR was conducted as described in Experimental Procedures using the primers listed in Table 1. Shown are the results as relative amounts of RNA in the non-MOZ-TIF2 leukemic blasts (clear bars) compared to the MOZ-TIF2 blasts (shaded bars). Stars represent a significant difference at P < 0.05 by the two-tailed Student T-test comparing RNA levels in the blasts of the patients without the MOZ-TIF2 fusion to the levels in the blasts with the MOZ-TIF2 fusion.