From: Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression
Compound
Dose (μmol/kg)
Observed Lethality
PCI-2012
20
1/3
30
0/3
40
3/3
PCI-2022
60
PCI-2050
25
PCI-2042
50
75
2/3