Table 2 Minimal recurrent regions altered in MPNSTs (n = 7)
From: DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH
Cytoband | Aberration | Start clone | End clone | Size (Mb) | Frequency | Observation |
|---|---|---|---|---|---|---|
1q21.1 | Gain | RP3-365I19 | RP11-544O24 | 1.2 | 3/7 | 1 sample with +1q |
1q24.1-q24.2 | Gain | RP11-525G13 | RP4-780M13 | 3.7 | 5/7 | 1 sample with +1q |
1q24.3-q25.1 | Gain | RP1-127D3 | RP5-830A10 | 3.5 | 5/7 | 1 sample with +1q |
2p15-p14 | Gain | RP11-52F10 | RP11-263L17 | 3.0 | 3/7 | 1 sample with +2p |
2q11.2-q13 | Gain | RP11-451C2 | RP11-368A17 | 11.0 | 4/7 | 1 sample with +2q |
3p26.2-p25.1 | Gain | RP11-95E11 | RP11-255O19 | 12.6 | 4/7 | 1 sample with +3, 1 sample with +3p |
3p22.1-p21.1 | Gain | RP11-437N10 | RP11-122D19 | 11.5 | 3/7 | 1 sample with +3, 1 sample with +3p |
3q27.2-q29 | Gain | RP11-110C15 | RP11-23M2 | 12.5 | 3/7 | 1 sample with +3 |
5p14.3 | Gain | RP11-28P24 | RP11-374E21 | 2.0 | 3/7 | 1 sample with +5 |
5q34-q35.3 | Gain | CTC-320C6 | RP11-281O15 | 15.2 | 4/7 | 1 sample with +5 |
6p22.1-p12.1 | Gain | RP11-373N24 | RP11-472M19 | 28.1 | 3/7 | 1 sample with +6p |
6p12.1-q12 | Gain | RP3-422B11 | RP11-349P19 | 7.8 | 3/7 | 1 sample with +6p, 1 sample with +6q |
7p21.2-p14.1 | Gain | RP11-512E16 | RP5-1178G13 | 26.3 | 3/7 | 1 sample with +7 |
7q11.23-q21.11 | Gain | RP11-313P13 | RP5-1057M1 | 7.4 | 4/7 | 1 sample with +7, 1 sample with +7q |
8p23.1-p12 | Gain | RP11-540E4 | RP11-473A17 | 22.9 | 5/7 | 2 samples with +8 |
8q11.23-q24.3 | Gain | RP11-53M11 | RP5-1056B24 | 90.5 | 3/7 | 2 samples with +8 |
9p24.3-p23 | Gain | RP11-48M17 | RP11-413D24 | 11.6 | 3/7 | 1 sample with +9p |
9p22.3-p21.2 | Loss | RP11-490C5 | RP11-20P5 | 12.8 | 3/7 | 2 samples with -9p |
9q21.32-q22.33 | Gain | RP11-541F16 | RP11-192E23 | 16.0 | 4/7 | |
9q34.11-q34.13 | Gain | RP11-202H3 | RP11-143H20 | 1.0 | 5/7 | |
11p13 | Loss | RP1-316D7 | RP4-607I7 | 1.5 | 4/7 | |
11q22.3-q23.1 | Loss | RP11-2I22 | RP11-11N15 | 7.7 | 3/7 | |
11q23.2-q23.3 | Loss | RP11-212D19 | RP11-142I2 | 7.0 | 3/7 | |
12p13.32-p13.31 | Gain | RP11-543P15 | RP11-277E18 | 4.8 | 3/7 | 1 sample with +12 |
12q12-q13.11 | Gain | RP11-333D23 | RP11-89H19 | 9.3 | 3/7 | 1 sample with +12 |
12q13.3-q15 | Gain | RP11-474N8 | RP11-101K2 | 14.2 | 4/7 | 1 sample with +12 |
12q21.2-q21.31 | Gain | RP11-26L7 | RP11-268A19 | 3.3 | 3/7 | 1 sample with +12 |
12q22 | Gain | RP11-24I19 | RP11-372G13 | 0.8 | 3/7 | 1 sample with +12 |
12q22-q23.3 | Gain | RP11-410A13 | RP11-415D21 | 9.1 | 3/7 | 1 sample with +12 |
13q12.11-q12.12 | Gain | RP11-76K19 | RP11-760M1 | 3.9 | 3/7 | 1 sample with +13 |
13q13.1-q14.3 | Gain | RP11-141M1 | RP11-327P2 | 18.5 | 3/7 | 1 sample with +13 |
13q22.1-q22.2 | Gain | RP11-552M6 | RP11-332E3 | 2.1 | 4/7 | 1 sample with +13 |
14q21.3-q23.3 | Loss | RP11-346L24 | RP11-430G13 | 15.3 | 3/7 | |
14q24.3-q32.33 | Gain | RP11-61F4 | RP11-417P24 | 27.9 | 3/7 | 1 sample with +14 |
16p13.3-p13.2 | Gain | RP11-344L6 | RP11-148F10 | 7.9 | 4/7 | 2 samples with +16 |
16p13.12-p13.11 | Gain | RP11-82O18 | RP11-489O1 | 0.9 | 4/7 | 2 samples with +16 |
16q21-q23.2 | Gain | RP11-148F12 | RP11-437L22 | 18.2 | 3/7 | 2 samples with +16 |
17q23.2-q25.3 | Gain | RP11-112J9 | RP11-567O16 | 26.2 | 5/7 | |
19p13.3-p13.2 | Gain | CTB-31C16 | RP11-492L14 | 4.9 | 4/7 | 2 samples with +19p |
22q12.3-q13.2 | Gain | LL22NC01-132D12 | RP3-437M21 | 6.1 | 3/7 |