Figure 2
From: Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma
Methylation frequency and methylation extent in esophageal tissues. Methylation of each gene was measured in multiple biopsies of squamous mucosa (S, n = 19) from seven patients without BE, single biopsies of squamous mucosa (S-BE, n = 16) and multiple biopsies of columnar mucosa (BE, n = 40) from 18 patients with BE, single biopsies of squamous mucosa (S-EAC, n = 21), high grade dysplastic Barrett's (D-EAC, n = 7) and tumor (EAC, n = 37) from 38 patients with EAC. The methylation was graded as unmethylated (white), methylated 1 (yellow), 2 (red), or 3 (blue), as described in the Materials and Methods.