Figure 1From: Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markersRepresentative methylation results in colorectal tumors and normal mucosa. Results of CDKN2A, CRABP1, HOXA9, and RUNX3 in selected samples are shown. Positive controls (POS): NB, normal blood, for the unmethylated reaction and IVD, in vitro methylated DNA, for methylated reaction. Negative controls: dH2O. U: unmethylated alleles, M: methylated alleles. The ladder (left lane) is the EZ Loadâ„¢ 100 bp Molecular Ruler (BioRad, Hercules, CA, USA).Back to article page