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Figure 3 | Molecular Cancer

Figure 3

From: Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy

Figure 3

Correlation between BLI, US and direct tumor volume determination in hepatic tumors. MC38Luc1 cells (5 × 105) were injected in the liver of C57BL/6 mice (n = 20), and tumor progression was evaluated weekly by either BLI, US or direct tumor measurement through laparotomy or necropsy. A – Tumor volume determined by direct measurement (calliper, black circles) or US (black squares) over time. Volumes are indicated in the left Y axis. Light emission quantified by BLI is represented as a dotted line and the scale corresponds to (photons/s) × 103 in the right Y axis. Error bars represent standard deviations. B.-Correlation between tumor volumes determined by US (X axis) and direct measurement after necropsy (calliper, Y axis) one month after cell implantation. C-D – Correlation between light emission and direct tumor measurement 2 weeks (C) or 3 weeks (D) after cell implantation (log10 conversion of values).

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Molecular Cancer

ISSN: 1476-4598