From: Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells
Cells with viral particles
Multinucleated cells
Nucleus
+
-
Condensed chromatin
Normal
None
0
100
6
2
98
Paclitaxel 1 μM
22
11 (3*)
89
ReoT3D (MOI = 20)
37
63
3
4 (1*)
96
ReoT3D (MOI = 20) + Paclitaxel 1 μM
16
84
8
23 (17*)
77 (26§)