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Figure 2 | Molecular Cancer

Figure 2

From: Dasatinib reverses Cancer-associated Fibroblasts (CAFs) from primary Lung Carcinomas to a Phenotype comparable to that of normal Fibroblasts

Figure 2

Effect of Dasatinib on gene expression. Heatmap of transcripts regulated by Dasatinib. Cell cycle related transcripts are shown in the left panel and transcripts not related to cell cycle in the right panel. Nine CAF strains isolated from 9 different lung carcinoma specimens were incubated with or without Dasatinib for 48 hours and analyzed with microarrays. Transcripts regulated by Dasatinib were identified by a significant 2fold change. The relative expression levels for a gene among the samples are indicated by green for low value and by red for high value. Each row represents a transcript; each column represents one sample (see also: Additional file 3, Table S2).

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Molecular Cancer

ISSN: 1476-4598