Skip to main content
Figure 3 | Molecular Cancer

Figure 3

From: SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

Figure 3

SOX11 DNA methylation and protein expression in primary lymphoma samples. Methylation patterns of SOX11 promoter in clinical specimens was determined by bisulfite sequencing of individual alleles and correlated to SOX11 protein expression. Every row represents a unique allele and the columns represent a potentially methylated CpG site. a) In MCL samples, the promoter stays unmethylated and SOX11 is detectable. b) The lack of SOX11 protein in FL and DLBCL is accompanied by 50-100% methylated alleles.

Back to article page

Molecular Cancer

ISSN: 1476-4598