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Table 4 Exons that are significantly changed in PTEN null and WT mice following SF-rich diets (LSF, HSF) and control diet (CO).

From: The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer

Comparison

Five weeks

Eight weeks

 

p < 0.11

p < 0.051

p < 0.011

p < 0.11

p < 0.051

p < 0.011

WT

      

LSF vs CO

0

0

0

0

0

0

HSF vs CO

3

0

0

0

0

0

PTEN null

      

LSF vs CO

18

6

1

106

31

0

HSF vs CO

318

37

2

94

24

3

Interaction

      

PTEN null CO vs WT CO

2

0

0

36

22

0

PTEN null LSF vs WT CO

51

16

1

602

2872

28

PTEN null HSF vs WT CO

4

1

1

872

2672

35

  1. 1 Benjamini and Hochberg adjusted P-values between the two groups.
  2. 2 Details of these exons are provided in Additional file 7 - Table S7.
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Molecular Cancer

ISSN: 1476-4598