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Table 1 Histological diagnosis of liver tissue from rats sacrificed at different time point

From: Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat

DENA Administration

Group

Histological diagnosis (no. animals)

  

Healthy

Fibrosis stage

HCC

   

F1-2

F3

F4 (cirrhosis)

 
 

control

3

    

week 0

DENA

2

    
 

control

3

    

week 4

DENA

 

6

   
 

control

3

    

week 6

DENA

 

12

   
 

control

3

    

week 9

DENA

  

11

4

 
 

control

3

    

week 14

DENA

   

5

2

 

control

6

    

week 18

DENA

    

13

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Molecular Cancer

ISSN: 1476-4598