Table 3 Results of univariate analysis for factors associated with advanced HCC stage at diagnosis
From: Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
Variable | AJCC/UICC stage I-II | AJCC/UICC stage III-IV | p value |
|---|---|---|---|
Male gender | 66.7% | 71.4% | 0.80 |
Age (years) | 69.4 ± 8.0 | 60 ± 18.1 | 0.20 |
Multiple tumor nodules | 44.4% | 42.9% | 0.94 |
Diameter of the biggest nodule (cm) | 6.7 ± 4.4 | 9.8 ± 4.0 | 0.10 |
Viral infection | 22.2% | 28.6% | 0.73 |
Cirrhosis | 44.4% | 28.6% | 0.43 |
Poorly differentiated HCC (G4) | 0% | 50% | 0.01 |
Macrovascular invasion | 22.2% | 64.3% | 0.04 |
Mir-199a expression (median value) | 0.07 | 0.36 | 0.17 |
DDR1 expression (median value) | 1.54 | 5.05 | 0.01 |