Figure 3
From: I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma
ML120B:vincristine combination induces cell cycle arrest and apoptosis. Flow cytometric analysis of cell cycle was done following PI staining of WSU-FSCCL cells. A. WSU-FSCCL cells were exposed to vincristine (V) for the indicated times and concentrations. B. WSU-FSCCL cells were pretreated with ML120B (M) for 60 minutes followed by vincristine (V) at the indicated concentrations and times. C. Apoptotic cells (Sub G0) analyzed by PI staining using flow cytometry in WSU-FSCCL for combinational treatments, Mean and standard error of mean (SEM). D. Apoptotic cells analyzed as in (C) in WSU-FSCCL cells treated with single agents.