Figure 3
From: Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression
ECM rigidity modulates N-myc expression in neuroblastoma cells and does so synergistically with retinoic acid. Quantitative-RT-PCR analysis of relative N-Myc expression in SK-N-DZ neuroblastoma cells cultured on 1.0 kPa versus 300 kPa collagen-coated PA gels in the presence or absence of 1 μM 13-cis RA for three days. Error bars represent standard deviations of 3 technical replicates.