Figure 2
From: The long non-coding RNA PCGEM1 is regulated by androgen receptor activity in vivo
Expression of PCGEM1 in response to AR activation in vitro . Expression levels (qPCR) of the labeled genes in A, LNCaP cells and B, VCaP cells treated with DHT at 10nM for 6 h, 12 h and 24 h. C, Expression (qPCR) of the labeled genes in LNCaP cells at 6 h, 12 h and 24 h after treatment with R1881 (10nM) or D, with a super-physiological dosage of DHT (100nM). For all the sub-figures, the columns represent mean expression value (2 independent experiments with each gene quantified in triplicates), bars represent standard deviation. NS, not significant; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 (unpaired, 2-tailed T test).