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Figure 4 | Molecular Cancer

Figure 4

From: In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAF V600E in melanoma

Figure 4

MITF and its target genes dysregulated by BRAF V600E driver mutation in primary tumor samples. A) and B) Boxplots show the relative gene expression level (median value) in tumor samples and fold changes (absolute value) between BRAF V600E and BRAF WT samples for:1) non-MITF target genes, 2) MITF ChIP-Seq binding targets), 3) MITF induced genes, and 4) MITF ChIP-Seq binding and induced targets.

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