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Figure 7 | Molecular Cancer

Figure 7

From: In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAF V600E in melanoma

Figure 7

BRAF V600E target genes in melanoma cell proliferation. Boxplots of shRNA values (measuring melanoma relative cell proliferation) for BRAF V600E target genes in down-regulation (D), up-regulation (U), and control genes (C). BRAF V600E target genes in down-regulations showed a statistically significant increase of melanoma cell proliferation relative to the control, whereas up-regulation genes exhibited a slight decrease in melanoma cell proliferation.

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