Figure 7From: In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAF V600E in melanoma BRAF V600E target genes in melanoma cell proliferation. Boxplots of shRNA values (measuring melanoma relative cell proliferation) for BRAF V600E target genes in down-regulation (D), up-regulation (U), and control genes (C). BRAF V600E target genes in down-regulations showed a statistically significant increase of melanoma cell proliferation relative to the control, whereas up-regulation genes exhibited a slight decrease in melanoma cell proliferation.Back to article page