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Fig. 2 | Molecular Cancer

Fig. 2

From: Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy

Fig. 2

Specificity of IMB-R1 for FGFR1. a, Binding of IMB-R1 and MAB765 to FGFR1 isoforms (representative blot from triplicate experiments). b, Affinity of IMB-R1 for FGFR isoforms (results are from triplicate experiments). c, Binding of FGFR to heparin in the presence or absence of IMB-R1 (results are from triplicate experiments). d, Binding of FGF2 to FGFR in the presence or absence of IMB-R1 (results are from triplicate experiments). e, FGFR phosphorylation stimulated by FGF2 in the presence or absence of IMB-R1 including the fold change of FGFR phosphorylation as determined by a comparison of means

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