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Fig. 5 | Molecular Cancer

Fig. 5

From: The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

Fig. 5

Scrib deficiency facilitates DMBA/TPA-induced epidermal lesion growth. a Diagram illustrating long-term two-step DMBA/TPA carcinogenesis approach initiated at 8 weeks of age. b Lesion-free percentage, (c) representative photographs of dorsal skin at 7, 14 and 26 weeks post-DMBA (scale bar: 1 cm, arrows indicate lesion onset), (d) lesion multiplicity plot (error bars = SEM) and (e) histogram to illustrate volume distribution of DMBA/TPA-induced epidermal lesions in Scrib +/+, Scrib +/fl and Scrib fl/fl mice (n = 12–16)

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Molecular Cancer

ISSN: 1476-4598