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Fig. 5 | Molecular Cancer

Fig. 5

From: Oral squamous cell carcinoma: microRNA expression profiling and integrative analyses for elucidation of tumourigenesis mechanism

Fig. 5

Inverse relationship of upregulated miRs with oncogenes, and downregulated miRs with tumour suppressor genes. Shown here are the interactions between (a) the over expressed miRNAs and tumour suppressor genes, and (b) the down regulated miRNAs and oncogenes. Data obtained by comparing the validated targets of each miRNA obtained from miRTarBase against the list of manually curated ‘Tumour suppressor genes’ or ‘Oncogenes’ retrieved from UniProt Knowledgebase. The flags represent miRNAs, the rectangular boxes represent their target genes and the discontinuous lines connecting them represent the interaction

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Molecular Cancer

ISSN: 1476-4598