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Fig. 5 | Molecular Cancer

Fig. 5

From: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer

Fig. 5

HOXA11-AS promotes β-catenin transcription by binding with WDR5. a, b Western blot analysis of WDR5 protein levels in BGC823 and SGC7901 cells after transfection with WDR5 or NC siRNA. c qRT-PCR analysis of β-catenin expression in BGC823 and SGC7901 cells after transfection with WDR5 or NC siRNA. d ChIP-qPCR analysis of WDR5, and H3K4me3 occupancy in the β-catenin promoter in BGC823 and SGC7901 cells. e ChIP-qPCR analysis of WDR5, and H3K4me3 occupancy in the β-catenin promoter in BGC823 and SGC7901 cells after transfection with HOXA11-AS or NC siRNA. *P < 0.05, **P < 0.01

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